Niclas G. Karlsson

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About

Niclas G. Karlsson is a leading researcher in glycobiology, with a primary focus on the structural and functional analysis of glycans in health and disease. His work centers on developing and applying high-throughput analytical methods to characterize N-glycosylation patterns, particularly in relation to pregnancy, immunity, and livestock management. A major contribution is his development of a robust UHPLC-based workflow for high-throughput plasma N-glycome analysis, a method that has become a cornerstone for large-scale glycomic studies (cited 23 times). Karlsson has also pioneered the application of glycomics to veterinary science, notably in his study of pregnancy-associated changes in IgG and serum N-glycosylation in the dromedary camel—a species of high economic value but low reproductive efficiency. This work demonstrates how glycosylation patterns can serve as non-invasive diagnostic biomarkers for reproductive status and health in camel livestock. By bridging cutting-edge analytical chemistry with applied agricultural biology, Karlsson’s research provides critical tools for improving animal management and understanding the fundamental roles of glycans in mammalian physiology.