Melissa Moore

Sofie Biosciences (United States), Institute for Molecular Medicine

Papers

Total Citations

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About

Melissa Moore is a leading figure in the field of automated radiochemistry, with a focused expertise in the development of advanced radiosynthesizers for positron-emission tomography (PET) tracer production. Her major contributions center on enhancing the safety, reproducibility, and flexibility of radiochemical synthesis through innovative automation. Moore is best known for her work on the ELIXYS system, a fully automated, three-reactor high-pressure radiosynthesizer designed for both development and routine production of diverse PET tracers. This platform significantly reduces operator radiation exposure and ensures consistent synthesis yields, addressing critical challenges in clinical and research settings. Her related work on plug-and-play modules for flexible radiosynthesis further expands the adaptability of automated systems, allowing for rapid reconfiguration for different tracers. While her most cited paper has garnered 28 citations, its impact is substantial within the niche field of radiochemistry instrumentation, where it serves as a foundational reference for automated synthesis design. Moore’s achievements represent a pivotal step toward safer, more efficient, and more versatile PET tracer production, directly supporting advances in molecular imaging and nuclear medicine.