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About

Marcello Di Martino is a leading figure in hepatobiliary and pancreatic surgery, with a focused expertise in minimally invasive techniques. His research rigorously compares robotic, laparoscopic, and open surgical approaches, aiming to define the optimal strategy for complex procedures. Di Martino’s major contributions include landmark meta-analyses and large-scale international studies that provide critical evidence on perioperative outcomes and cost-effectiveness. His 2021 meta-analysis on robotic versus laparoscopic distal pancreatectomies (27 citations) systematically evaluated both clinical results and financial implications, offering surgeons a comprehensive framework for decision-making. He further advanced the field by leading the IRON study (2024, 15 citations), a retrospective international multicenter investigation that directly compared robotic, laparoscopic, and open approaches for gallbladder cancer—a rare but aggressive disease. Most recently, his work on “Textbook Outcomes” (2025) has introduced a composite quality metric for gallbladder cancer surgery, setting a new standard for global benchmarking. With a career dedicated to refining surgical practice through robust data, Di Martino’s research is essential reading for surgeons and researchers seeking to understand the evolving landscape of minimally invasive hepatobiliary surgery.