Lingli Shi

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About

Lingli Shi is a leading voice in geriatric psychiatry, whose work has profoundly shaped our understanding of late-life depression (LLD) and its intersection with global health crises. Her research centers on the epidemiology, clinical phenotypes, and neurobiological underpinnings of mood disorders in older adults, with a particular focus on how social stressors—most notably the COVID-19 pandemic—exacerbate mental health vulnerabilities in aging populations. In her landmark 2023 paper, *Late-life depression: Epidemiology, phenotype, pathogenesis and treatment before and during the COVID-19 pandemic* (34 citations), Shi provides a comprehensive synthesis of how population aging and pandemic-related isolation have driven a worldwide surge in LLD. She critically distinguishes the unique clinical presentation of LLD from earlier-onset depression, highlighting its distinct cognitive and physical comorbidities, and offers an integrated framework for pathogenesis and treatment adaptation. This work has become an essential reference for clinicians and researchers navigating the post-pandemic mental health landscape. Through her rigorous scholarship, Shi is helping to redefine geriatric mental healthcare, ensuring that the emotional well-being of older adults remains a global priority.