Lesley Reeve
Papers
2
Total Citations
23
H-Index
2
About
Lesley Reeve is a leading researcher in the field of in vitro toxicology, with a specialized focus on the assessment of combustible tobacco products. Her key research areas center on the development and refinement of whole smoke exposure systems, particularly the VITROCELL® VC10®, to more accurately mimic in vivo conditions. Reeve’s major contributions include pioneering quantitative methods for dose assessment in in vitro evaluations, moving beyond traditional partitioned exposures (like total particulate matter) to study the toxicological impact of whole smoke. Her work on investigating multiple dosimetry techniques has been instrumental in establishing more physiologically relevant testing protocols, with her most-cited paper, "Investigation of multiple whole smoke dosimetry techniques using a VITROCELL®VC10® smoke exposure system" (2019), garnering 13 citations. This foundational study, along with her 2018 work on quantitative dose assessment (10 citations), has directly advanced the rigor and reproducibility of in vitro smoke exposure research. By enabling more accurate assessments of cytotoxicity and genotoxicity, Reeve’s achievements provide critical tools for regulatory science and product evaluation, making her a key figure in the evolution of tobacco product testing methodologies.
Research Focus
Key Achievements
Top Papers
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