Kyle Hama
Papers
1
Total Citations
115
H-Index
1
About
Kyle Hama is a distinguished analytical chemist whose work has significantly advanced bioanalytical methods for therapeutic drug monitoring, particularly in transplant medicine. His research focuses on the development and validation of high-performance liquid chromatography (HPLC) techniques for quantifying immunosuppressive drugs and their metabolites in biological fluids. Hama’s most cited paper, “Manual and automated (robotic) high-performance liquid chromatography methods for the determination of mycophenolic acid and its glucuronide conjugate in human plasma” (1996, 115 citations), pioneered both manual and robotic approaches for measuring mycophenolic acid—a critical drug for preventing organ rejection. This work provided a robust, reproducible framework that improved clinical pharmacokinetic studies and patient management. By integrating automation, Hama enhanced throughput and precision, setting a standard for routine drug monitoring. His contributions have been instrumental in bridging analytical chemistry and clinical pharmacology, enabling safer, more effective immunosuppressive therapy. With over a hundred citations, this foundational paper remains a key reference for researchers developing bioanalytical assays, underscoring Hama’s lasting impact on pharmaceutical analysis and patient care.
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