Irene Cumplido‐Mayoral

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About

Irene Cumplido‐Mayoral is a neuroscientist whose research focuses on the spatiotemporal dynamics of brain function, with a particular emphasis on the balance between cortical excitation and inhibition. Her most cited work, "Spatiotemporal Dynamics of Single and Paired Pulse TMS-EEG Responses" (2020, 22 citations), represents a significant methodological contribution to the field of non-invasive brain stimulation. In this study, she combined transcranial magnetic stimulation (TMS) with electroencephalography (EEG) to investigate how paired-pulse TMS can estimate cortical excitability and disentangle the relative contributions of inhibitory and excitatory neural networks. This work provides crucial insights into the physiological mechanisms underlying brain function and has implications for understanding neurological and psychiatric disorders where excitation-inhibition balance is disrupted. By advancing the TMS-EEG paradigm, Cumplido‐Mayoral has helped establish a more precise tool for probing cortical dynamics, offering researchers a window into the real-time interplay of neural circuits. Her research is foundational for developing targeted interventions in conditions such as epilepsy, schizophrenia, and autism spectrum disorders.