Guillaume B. E. Stewart-Jones
Papers
2
Total Citations
146
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2
About
Guillaume B. E. Stewart-Jones is a structural biologist whose work has significantly advanced our understanding of T-cell receptor (TCR) recognition and immune system architecture. His research focuses on the structural biology of immune receptors, particularly αβ T-cell receptors and their interactions with peptide-MHC complexes. Stewart-Jones made major contributions to the systematic production and structural analysis of soluble αβ T-cell receptors, developing methods that enabled high-resolution structural studies of these critical immune molecules. His most cited work, "A procedure for setting up high-throughput nanolitre crystallization experiments" (2003, 131 citations), established robotic crystallization protocols that dramatically reduced protein sample requirements and accelerated structural determination pipelines. This methodological innovation has been widely adopted in structural biology laboratories worldwide. Stewart-Jones also contributed to understanding how T-cell receptors recognize antigens, providing fundamental insights into adaptive immunity. His work has been instrumental in advancing structural immunology, with his crystallization techniques enabling numerous subsequent discoveries in immune receptor biology and vaccine design.
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Top Papers
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