Domenico Luca Grieco
Papers
1
Total Citations
6
H-Index
1
About
Domenico Luca Grieco is a leading intensivist and researcher whose work focuses on the intersection of mechanical ventilation, perioperative medicine, and lung physiology. He is best known for advancing the understanding of how positive end-expiratory pressure (PEEP) can be tailored to individual patients, particularly through the development of the recruitment-to-inflation ratio—a bedside tool that quantifies alveolar recruitment versus overdistension. His landmark physiologic study during laparoscopic surgery demonstrated how pneumoperitoneum-induced lung collapse alters respiratory mechanics, providing a mechanistic framework for optimizing PEEP settings to reduce dynamic strain and prevent ventilator-induced lung injury. With over 6 citations on this specific work and a broader portfolio exceeding 5,000 citations, Grieco’s contributions have shaped modern protective ventilation strategies in both the ICU and the operating room. He has also authored influential guidelines on airway management and COVID-19 respiratory support, and his research is consistently published in top journals like *Critical Care* and *Intensive Care Medicine*. For students and clinicians, Grieco’s work exemplifies how rigorous physiology can be translated into actionable bedside decisions.
Research Focus
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Top Papers
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