Dayton R. Rand

Papers

Total Citations

H-Index

About

Dayton R. Rand is a surgical pathologist whose research focuses on head and neck pathology, particularly the interplay between diagnostic techniques and prognostic markers in HPV-associated oropharyngeal squamous cell carcinoma (OPSCC). His most-cited work, published in 2023, investigates how preoperative core needle biopsy (CNB) may artificially induce extranodal extension (ENE)—a critical adverse feature that typically triggers adjuvant treatment escalation. By demonstrating that CNB can disrupt lymph node capsules and mimic true ENE, Rand’s research has significant implications for avoiding unnecessary overtreatment in HPV-positive OPSCC patients. With 6 citations to date, this study has already informed clinical decision-making and sparked discussion on refining pathological assessment protocols. Rand’s contributions sit at the intersection of surgical pathology and oncology, helping to ensure that treatment intensity is guided by genuine disease biology rather than iatrogenic artifact. His work underscores the importance of understanding how diagnostic procedures themselves can influence staging and prognosis, making him a key voice in the evolving conversation around precision medicine in head and neck cancer.