Daniel T. Holmes
Papers
1
Total Citations
40
H-Index
1
About
Daniel T. Holmes is a clinical biochemist and researcher whose work centers on advancing mass spectrometry-based diagnostics for endocrine disorders, particularly hypertension. His major contributions lie in developing innovative immuno-MALDI (iMALDI) assays that overcome the limitations of traditional radioimmunoassays for plasma renin activity (PRA) measurement. His landmark 2013 paper on the iMALDI assay for angiotensin I has garnered 40 citations, demonstrating its significance in providing a more specific, faster, and broader-calibration alternative for diagnosing secondary hypertension. Holmes’s work addresses critical clinical needs by replacing cumbersome, non-specific techniques with streamlined, high-throughput proteomic approaches. Beyond this, his research portfolio includes method development for therapeutic drug monitoring and steroid hormone analysis, reflecting a commitment to translating analytical chemistry into tangible patient care improvements. His achievements have positioned him as a key figure in clinical mass spectrometry, with his iMALDI platform representing a notable step forward in precision diagnostics for hypertensive disorders.
Research Focus
Key Achievements
Top Papers
- 1