Chun‐Wan Yen

Gene Therapy Laboratory

Papers

2

Total Citations

95

H-Index

2

About

Chun-Wan Yen is a leading researcher in the field of lipid nanoparticle (LNP) technology, with a primary focus on the rational design and high-throughput development of nucleic acid delivery systems. Her work is pivotal in advancing the clinical translation of gene therapies and mRNA vaccines. Dr. Yen’s major contributions include pioneering automated, high-throughput methods for preparing and characterizing oligonucleotide-loaded LNPs, a breakthrough that significantly accelerates formulation screening and optimization. Her 2021 paper on this topic, which has garnered 63 citations, is a cornerstone for researchers seeking to streamline LNP production. She has also elucidated the critical role of non-ionizable lipids and phase mixing methods in dictating the structural properties of LNPs, as detailed in her 2023 work (32 citations). By systematically investigating how formulation parameters influence nanoparticle architecture and performance, Dr. Yen provides essential guidelines for designing more stable and effective delivery vehicles. Her research bridges fundamental materials science with practical pharmaceutical engineering, making her a key figure in the next generation of nanomedicine.

Research Focus

Key Achievements

2
H-Index
2
Papers
95
Total Citations
48
Avg Citations/Paper
🏆 Most Cited Paper
Automated high-throughput preparation and characterization of oligonucleotide-loaded lipid nanoparticles
63 citations · 2021
📈 Most Prolific Year: 2021 (1 Papers)
🤝 Key Collaborators: 22
🏛 Institutions: Gene Therapy Laboratory

Top Papers

  1. 1
  2. 2

Key Collaborators

Contact & Links

Available for collaboration
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