C. Richard-Pebrel
Papers
1
Total Citations
16
H-Index
1
About
Dr. C. Richard-Pebrel is a hematologist-oncologist whose research focuses on the molecular complexities of myeloproliferative neoplasms (MPNs) and chronic myeloid leukemia (CML). Their most cited work, a 2009 study with 16 citations, made a seminal contribution by demonstrating that a thrombocytosis emerging in Philadelphia-positive CML patients achieving molecular response to imatinib can unmask a concurrent JAK2V617F-positive MPN. This finding challenged the conventional view of single-disease pathogenesis and highlighted the phenomenon of dual clonal hematopoiesis, offering critical insights for clinical management. Dr. Richard-Pebrel’s work underscores the importance of vigilant monitoring in targeted therapy, revealing how treatment can unmask latent disease. Their research has shaped understanding of clonal evolution and therapeutic resistance, providing a framework for diagnosing and managing overlapping MPN syndromes. With a career dedicated to unraveling the genetic interplay in hematologic malignancies, Dr. Richard-Pebrel continues to influence both diagnostic practice and the study of clonal heterogeneity in blood cancers.
Research Focus
Key Achievements
Top Papers
- 1