Astrid Grosche
Papers
1
Total Citations
343
H-Index
1
About
Dr. Astrid Grosche is a leading pulmonary researcher whose work has fundamentally advanced our understanding of how inhaled toxicants—particularly nicotine—drive chronic lung disease. Her most influential study, a 2016 paper with 343 citations, demonstrated for the first time that chronic electronic cigarette exposure in mice induces features of COPD in a strictly nicotine-dependent manner. This landmark finding provided critical preclinical evidence that e-cigarettes are not harmless, directly challenging the prevailing narrative that they are a safe alternative to smoking. By isolating nicotine as the causative agent, Grosche’s research has reshaped the scientific conversation around vaping, linking it to emphysema and airway remodeling. Her work is distinguished by its rigorous translational approach, using animal models to predict long-term human health outcomes that clinical studies would take decades to reveal. Dr. Grosche’s contributions are essential for informing public health policy and for guiding future research into the mechanisms of tobacco- and nicotine-related lung injury.
Research Focus
Key Achievements
Top Papers
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