Anna-Katharina Pumm

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About

Anna-Katharina Pumm is a pioneering researcher at the forefront of DNA nanotechnology and biophysics, with a focus on engineering synthetic molecular machines that operate at the nanoscale. Her most notable contribution is the experimental realization of a DNA turbine powered by a transmembrane potential across a solid-state nanopore—a landmark achievement published in 2023 that has already garnered 51 citations. This work demonstrates the first functional synthetic nanoscale turbine, drawing inspiration from biological rotary motors like ATP synthase, and opens new avenues for harnessing electrochemical gradients to drive artificial nanomachines. Pumm’s research bridges structural DNA nanotechnology with single-molecule biophysics, enabling precise control over molecular motion and energy transduction. Her innovative approach has significant implications for developing nanoscale devices for sensing, drug delivery, and energy conversion. By combining elegant DNA origami design with nanopore technology, she has established a new paradigm for creating active, fuel-driven nanorotors. Her work is widely recognized for its creativity and technical rigor, positioning her as a rising leader in the field of synthetic molecular machinery.